The Effect of Copper Ions on Clot Lysis Time in the Fibrinolytic Assay of Streptokinase

Alwin B. Bogert

doi:10.1055/s-0038-1656246

Thrombosis and Haemostasis, Table of Contents

Thromb Haemost 1965; 13(02): 477-483
DOI: 10.1055/s-0038-1656246

Originalarbeiten — Original Articles — Travaux Originaux

Schattauer GmbH Schattauer

The Effect of Copper Ions on Clot Lysis Time in the Fibrinolytic Assay of Streptokinase

Alwin B. Bogert

¹Lederle Laboratories Division, American Cyanamid Company, Pearl River, N. Y.

› Author Affiliations

Abstract

Summary

Experiments were conducted to determine why different lots of Borate Buffer reagent affect the clot lysis times obtained in the fibrinolytic assay of Streptokinase. Minerals naturally occurring in distilled water were screened individually to determine their influence on lysis. Copper was found to have a very pronounced effect in this regard on the fibrinolytic system in that low levels reduce the lysis time and high levels increase it.

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References

References
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